Melanoma microinvasivo: approcci farmacoterapeutici cutanei.

L’escissione chirurgica è il trattamento di scelta per i melanomi primari e la radioterapia è l’alternativa accettata per il sottogruppo di lesioni non suscettibili di intervento chirurgico. Con il recente aumento dell’incidenza del melanoma, soprattutto negli anziani, c’è un numero crescente di casi che non sono né suscettibili di chirurgia né radioterapia. In questo articolo, esaminiamo gli approcci farmacoterapeutici al melanoma microinvasivo (melanoma invasivo in fase di crescita radiale) che potrebbero essere considerati in tali circostanze. Non ci sono farmaci approvati per il trattamento del melanoma primario e non sono stati effettuati studi randomizzati controllati con 5 o più anni di follow-up. Gli studi limitati e le numerose serie di casi presenti in letteratura sul trattamento farmacologico del melanoma primario si sono concentrati sulle terapie topiche.

Di conseguenza, forniamo una revisione dei potenziali agenti farmacoterapeutici nel trattamento del melanoma microinvasivo estrapolando dalla letteratura limitata disponibile sull’uso di fluorouracile, acido azelaico, derivati ​​dell’acido retinoico, interferone (IFN) -α, imiquimod e altri agenti per melanoma in situ, melanoma invasivo e metastasi di melanoma epidermotropico. La nostra revisione indica che il fluorouracile topico e la tretinoina non sono efficaci come agenti singoli. L’efficacia di acido azelaico, tazarotene, cidofovir e IFN-α intralesionale, interleuchina-2 e IFN-β non è definita. Imiquimod è l’agente più studiato e promettente; tuttavia, il dosaggio ottimale, il regime terapeutico e i tassi di sopravvivenza non sono noti. A fronte di una crescente domanda di trattamenti non chirurgici, sono necessari studi clinici formali per accertare il ruolo degli agenti farmacoterapeutici nel trattamento del melanoma microinvasivo.

Un rapporto sullo stato del tazarotene topico nella gestione dell’acne vulgaris.

Il tazarotene è un retinoide sintetico che, a seconda della concentrazione e del veicolo, è approvato dalla Food and Drug Administration statunitense per il trattamento topico dell’acne vulgaris (AV) e della psoriasi a placche. Il tazarotene è anche usato come trattamento aggiuntivo per specifiche manifestazioni cliniche di pelle cronicamente fotodanneggiata (rughe sottili del viso, ipopigmentazione e iperpigmentazione facciale chiazzata e lentiggini facciali benigne), insieme a una cura completa della pelle e fotoprotezione dalla luce solare. La formulazione in gel è stata rilasciata negli Stati Uniti nel 1997, con la formulazione in crema resa disponibile nel 2000. Sono disponibili molteplici studi a sostegno dell’uso efficace e sicuro del tazarotene topico per ciascuna delle sue indicazioni.

Questo articolo fornisce una panoramica della farmacologia del tazarotene applicato per via topica, discutendo in particolare informazioni aggiornate sull’efficacia, tollerabilità e sicurezza del tazarotene topico per AV, inclusi studi in monoterapia e terapia di combinazione. Il tazarotene topico 0,1% in entrambe le formulazioni è altamente efficace nel ridurre le lesioni dell’acne infiammatorie e non infiammatorie e può essere utilizzato in combinazione con altri agenti topici, comprese le formulazioni contenenti perossido di benzoile o dapsone 5% gel. Sebbene molti pazienti tollerino l’uso del tazarotene topico senza problemi o preoccupazioni significativi, alcuni pazienti manifestano reazioni di tollerabilità al sito di applicazione, che di solito possono essere gestite con un’adeguata cura della pelle e sono meno frequenti con la formulazione in crema.

Tazarotene topico per il trattamento dell’ectropion nell’ittiosi.

OBBIETTIVO
L’ectropion è una complicazione di alcuni sottotipi di ittiosi ed è spesso associata a sostanziali conseguenze mediche e cosmetiche. Al momento non esiste uno standard di cura per il trattamento dell’ectropion in questa popolazione. I retinoidi causano disesione e assottigliamento dello strato corneo, riducendo così l’ipercheratosi che probabilmente è alla base dell’ectropion nei pazienti con ittiosi. In quanto tali, i retinoidi forniscono un potenziale trattamento efficace per l’ectropion in questo gruppo di pazienti.

METODI
Descriviamo un paziente con ittiosi recessiva per il quale l’applicazione quotidiana di tazarotene topico ha prodotto un miglioramento rapido e persistente dell’ectropion bilaterale della palpebra inferiore senza effetti avversi.

Tissue factor pathway inhibitor 2
AP79755	SAB	1mg	2640 EUR
Tissue Factor Pathway Inhibitor TFPI
MBS606041-01mg	MyBiosource	0.1mg	835 EUR
Tissue Factor Pathway Inhibitor TFPI
MBS606041-5x01mg	MyBiosource	5x0.1mg	3610 EUR
Tissue Factor Pathway Inhibitor (TFPI)
MBS6508350-01mg	MyBiosource	0.1mg	860 EUR
Tissue Factor Pathway Inhibitor (TFPI)
MBS6508350-5x01mg	MyBiosource	5x0.1mg	3725 EUR
Sheep anti-Human Tissue Factor Pathway Inhibitor
MBS135479-1mg	MyBiosource	1mg	315 EUR
Sheep anti-Human Tissue Factor Pathway Inhibitor
MBS135479-5mg	MyBiosource	5mg	580 EUR
Sheep anti-Human Tissue Factor Pathway Inhibitor
MBS135479-5x5mg	MyBiosource	5x5mg	2420 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody
20-abx103325	Abbexa	Ask for price Ask for price Ask for price Ask for price Ask for price	100 ug 10 ug 1 mg 200 ug 50 ug
Tissue Factor Pathway Inhibitor (TFPI) Antibody
20-abx103326	Abbexa	Ask for price Ask for price Ask for price Ask for price Ask for price	100 ug 10 ug 1 mg 200 ug 50 ug
Tissue Factor Pathway Inhibitor (TFPI) Antibody
20-abx103328	Abbexa	Ask for price Ask for price Ask for price Ask for price Ask for price	100 ug 10 ug 1 mg 200 ug 50 ug
Tissue Factor Pathway Inhibitor (TFPI) Antibody
20-abx103329	Abbexa	Ask for price Ask for price Ask for price Ask for price Ask for price	100 ug 10 ug 1 mg 200 ug 50 ug
Tissue Factor Pathway Inhibitor (TFPI) Antibody
20-abx104947	Abbexa	Ask for price Ask for price Ask for price Ask for price Ask for price	100 ug 10 ug 1 mg 200 ug 50 ug
Tissue Factor Pathway Inhibitor (TFPI) Antibody
20-abx129517	Abbexa	Ask for price Ask for price Ask for price Ask for price Ask for price	100 ug 10 ug 1 mg 200 ug 50 ug
Tissue Factor Pathway Inhibitor (TFPI) Antibody
20-abx132084	Abbexa	Ask for price Ask for price Ask for price Ask for price Ask for price	100 ug 1 mg 200 ug 20 ug 50 ug
Tissue Factor Pathway Inhibitor (TFPI) Antibody
20-abx132085	Abbexa	Ask for price Ask for price Ask for price Ask for price Ask for price	100 ug 1 mg 200 ug 20 ug 50 ug
Tissue Factor Pathway Inhibitor (TFPI) Antibody
20-abx132086	Abbexa	Ask for price Ask for price Ask for price Ask for price Ask for price	100 ug 1 mg 200 ug 20 ug 50 ug
Tissue Factor Pathway Inhibitor (TFPI) Antibody
20-abx116110	Abbexa	Ask for price Ask for price	150 ul 50 ul
Tissue Factor Pathway Inhibitor (TFPI) Antibody
20-abx001368	Abbexa	Ask for price Ask for price Ask for price Ask for price	100 ul 200 ul 20 ul 50 ul
Tissue Factor Pathway Inhibitor (TFPI) Antibody
20-abx174804	Abbexa	Ask for price Ask for price	1 mg 200 ug
Tissue Factor Pathway Inhibitor (TFPI) Antibody
abx433382-200ul	Abbexa	200 ul	460.8 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody
abx238634-100ug	Abbexa	100 ug	661.2 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody
20-abx323593	Abbexa	Ask for price Ask for price	100 ug 50 ug
Tissue Factor Pathway Inhibitor (TFPI) Antibody
abx116110-100g	Abbexa	100 µg	Ask for price
Tissue Factor Pathway Inhibitor (TFPI) Antibody
abx116110-10g	Abbexa	10 µg	612.5 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody
abx116110-200g	Abbexa	200 µg	Ask for price
Tissue Factor Pathway Inhibitor (TFPI) Antibody
abx129517-100l	Abbexa	100 µl	262.5 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody
abx129517-1ml	Abbexa	1 ml	687.5 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody
abx129517-200l	Abbexa	200 µl	325 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody
abx174804-25mg	Abbexa	25 mg	Ask for price
Tissue Factor Pathway Inhibitor (TFPI) Antibody
abx174804-5mg	Abbexa	5 mg	775 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody
abx238634-100l	Abbexa	100 µl	Ask for price
Tissue Factor Pathway Inhibitor (TFPI) Antibody
abx238634-50l	Abbexa	50 µl	350 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody
abx132084-100tests	Abbexa	100 tests	237.5 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody
abx132085-01mg	Abbexa	0.1 mg	275 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody
abx132086-01mg	Abbexa	0.1 mg	237.5 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody
abx349963-96tests	Abbexa	96 tests	287.5 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody
abx433382-100g	Abbexa	100 µg	387.5 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody
abx323593-100g	Abbexa	100 µg	250 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody
abx323593-50g	Abbexa	50 µg	187.5 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody
abx001368-100l	Abbexa	100 µl	400 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody
abx001368-20l	Abbexa	20 µl	175 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody
abx001368-50l	Abbexa	50 µl	275 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody
abx104947-100g	Abbexa	100 µg	475 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody
abx104947-20g	Abbexa	20 µg	212.5 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody
abx104947-50g	Abbexa	50 µg	250 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody
abx103325-100g	Abbexa	100 µg	475 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody
abx103325-20g	Abbexa	20 µg	212.5 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody
abx103325-50g	Abbexa	50 µg	250 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody
abx103326-100g	Abbexa	100 µg	475 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody
abx103326-20g	Abbexa	20 µg	212.5 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody
abx103326-50g	Abbexa	50 µg	250 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody
abx103328-100g	Abbexa	100 µg	725 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody
abx103328-20g	Abbexa	20 µg	262.5 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody
abx103328-50g	Abbexa	50 µg	337.5 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody
abx103329-100g	Abbexa	100 µg	725 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody
abx103329-20g	Abbexa	20 µg	262.5 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody
abx103329-50g	Abbexa	50 µg	337.5 EUR
Tissue Factor Pathway Inhibitor 2 (TFPI2)
MBS6508351-01mg	MyBiosource	0.1mg	845 EUR
Tissue Factor Pathway Inhibitor 2 (TFPI2)
MBS6508351-5x01mg	MyBiosource	5x0.1mg	3660 EUR
Tissue Factor Pathway Inhibitor 2 (TFPI2)
MBS6508352-01mg	MyBiosource	0.1mg	875 EUR
Tissue Factor Pathway Inhibitor 2 (TFPI2)
MBS6508352-5x01mg	MyBiosource	5x0.1mg	3785 EUR
Tissue Factor Pathway Inhibitor 2 Protein
20-abx263563	Abbexa	Ask for price Ask for price Ask for price	1 µg 50 ug 5 ug
Tissue Factor Pathway Inhibitor Rabbit mAb
E2R27344	EnoGene	100ul	255 EUR
Description: Available in various conjugation types.
Tissue Factor Pathway Inhibitor Rabbit mAb
E2R27346	EnoGene	100ul	255 EUR
Description: Available in various conjugation types.
Human Tissue factor pathway inhibitor (TFPI)
1-CSB-EP023437HU	Cusabio	Ask for price Ask for price Ask for price Ask for price Ask for price Ask for price	100ug 10ug 1MG 200ug 500ug 50ug
Description: Recombinant Human Tissue factor pathway inhibitor(TFPI),partial expressed in E.coli
Tissue Factor Pathway Inhibitor 2 Protein
abx263563-10mg	Abbexa	10 mg	1600 EUR
Tissue Factor Pathway Inhibitor 2 Protein
abx263563-1mg	Abbexa	1 mg	225 EUR
Tissue Factor Pathway Inhibitor 2 Protein
abx263563-5mg	Abbexa	5 mg	325 EUR
Horse TFPI (Tissue factor pathway inhibitor)
MBS766164-10x96StripWells	MyBiosource	10x96-Strip-Wells	3900 EUR
Horse TFPI (Tissue factor pathway inhibitor)
MBS766164-48StripWells	MyBiosource	48-Strip-Wells	340 EUR
Horse TFPI (Tissue factor pathway inhibitor)
MBS766164-5x96StripWells	MyBiosource	5x96-Strip-Wells	2045 EUR
Horse TFPI (Tissue factor pathway inhibitor)
MBS766164-96StripWells	MyBiosource	96-Strip-Wells	455 EUR
Rabbit Tissue factor pathway inhibitor (TFPI)
1-CSB-YP023437RB	Cusabio	Ask for price Ask for price Ask for price Ask for price Ask for price Ask for price	100ug 10ug 1MG 200ug 500ug 50ug
Description: Recombinant Rabbit Tissue factor pathway inhibitor(TFPI) expressed in Yeast
Active Tissue Factor Pathway Inhibitor (TFPI)
APA394Hu61	Cloud-Clone	10ug	360 EUR
Rabbit Tissue factor pathway inhibitor (TFPI)
1-CSB-EP023437RB	Cusabio	Ask for price Ask for price Ask for price Ask for price Ask for price Ask for price	100ug 10ug 1MG 200ug 500ug 50ug
Description: Recombinant Rabbit Tissue factor pathway inhibitor(TFPI) expressed in E.coli
Rabbit Tissue factor pathway inhibitor (TFPI)
1-CSB-BP023437RB	Cusabio	Ask for price Ask for price Ask for price Ask for price Ask for price Ask for price	100ug 10ug 1MG 200ug 500ug 50ug
Description: Recombinant Rabbit Tissue factor pathway inhibitor(TFPI) expressed in Baculovirus
Rabbit Tissue factor pathway inhibitor (TFPI)
1-CSB-MP023437RB	Cusabio	Ask for price Ask for price Ask for price Ask for price	100ug 1MG 200ug 500ug
Description: Recombinant Rabbit Tissue factor pathway inhibitor(TFPI) expressed in Mammalian cell
Tissue Factor Pathway Inhibitor (TFPI) Protein
20-abx261170	Abbexa	Ask for price Ask for price Ask for price	1 mg 20 ug 5 ug
Tissue Factor Pathway Inhibitor (TFPI) Protein
abx261170-10g	Abbexa	10 µg	325 EUR
Tissue Factor Pathway Inhibitor (TFPI) Protein
abx261170-2g	Abbexa	2 µg	225 EUR
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
20-abx103659	Abbexa	Ask for price Ask for price Ask for price Ask for price Ask for price	100 ug 10 ug 1 mg 200 ug 50 ug
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
20-abx103660	Abbexa	Ask for price Ask for price Ask for price Ask for price Ask for price	100 ug 10 ug 1 mg 200 ug 50 ug
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
20-abx103661	Abbexa	Ask for price Ask for price Ask for price Ask for price Ask for price	100 ug 10 ug 1 mg 200 ug 50 ug
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
20-abx103662	Abbexa	Ask for price Ask for price Ask for price Ask for price Ask for price	100 ug 10 ug 1 mg 200 ug 50 ug
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
abx122715-100ug	Abbexa	100 ug	469.2 EUR
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
20-abx006327	Abbexa	Ask for price Ask for price Ask for price Ask for price	100 ul 200 ul 20 ul 50 ul
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
20-abx210903	Abbexa	Ask for price Ask for price	100 ul 50 ul
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
20-abx174805	Abbexa	Ask for price Ask for price	1 mg 200 ug
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
20-abx322259	Abbexa	Ask for price Ask for price	100 ul 50 ul
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
20-abx323594	Abbexa	Ask for price Ask for price	100 ug 50 ug
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
20-abx320289	Abbexa	Ask for price Ask for price	100 ul 50 ul
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
20-abx339482	Abbexa	Ask for price Ask for price	100 ul 50 ul
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
abx210903-100l	Abbexa	100 µl	350 EUR
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
abx210903-50l	Abbexa	50 µl	250 EUR
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
abx174805-100g	Abbexa	100 g	750 EUR
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
abx174805-500g	Abbexa	500 g	Ask for price
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
abx122715-100l	Abbexa	100 µl	Ask for price
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
abx122715-20l	Abbexa	20 µl	337.5 EUR
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
abx122715-50l	Abbexa	50 µl	Ask for price
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
abx339482-100g	Abbexa	100 µg	Ask for price
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
abx339482-20g	Abbexa	20 µg	250 EUR
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
abx339482-50g	Abbexa	50 µg	350 EUR
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
abx323594-100g	Abbexa	100 µg	250 EUR
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
abx323594-50g	Abbexa	50 µg	187.5 EUR
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
abx320289-100l	Abbexa	100 µl	350 EUR
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
abx320289-50l	Abbexa	50 µl	237.5 EUR
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
abx344660-100l	Abbexa	100 µl	350 EUR
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
abx344660-50l	Abbexa	50 µl	250 EUR
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
abx375235-96tests	Abbexa	96 tests	337.5 EUR
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
abx322259-100g	Abbexa	100 µg	350 EUR
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
abx322259-50g	Abbexa	50 µg	237.5 EUR
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
abx006327-100g	Abbexa	100 µg	275 EUR
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
abx006327-10g	Abbexa	10 µg	175 EUR
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
abx006327-200g	Abbexa	200 µg	400 EUR
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
abx103659-100g	Abbexa	100 µg	712.5 EUR
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
abx103659-20g	Abbexa	20 µg	262.5 EUR
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
abx103659-50g	Abbexa	50 µg	325 EUR
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
abx103660-100g	Abbexa	100 µg	725 EUR
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
abx103660-20g	Abbexa	20 µg	262.5 EUR
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
abx103660-50g	Abbexa	50 µg	337.5 EUR
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
abx103661-100g	Abbexa	100 µg	775 EUR
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
abx103661-20g	Abbexa	20 µg	275 EUR
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
abx103661-50g	Abbexa	50 µg	350 EUR
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
abx103662-100g	Abbexa	100 µg	850 EUR
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
abx103662-20g	Abbexa	20 µg	287.5 EUR
Tissue Factor Pathway Inhibitor 2 (TFPI2) Antibody
abx103662-50g	Abbexa	50 µg	375 EUR
Eukaryotic Tissue Factor Pathway Inhibitor (TFPI)
EPA394Hu61	Cloud-Clone	10ug	200 EUR
Eukaryotic Tissue Factor Pathway Inhibitor (TFPI)
RPU58805-100ug	Biomatik Corporation	100ug	672 EUR
Eukaryotic Tissue Factor Pathway Inhibitor (TFPI)
RPU58805-1mg	Biomatik Corporation	1mg	3120 EUR
Eukaryotic Tissue Factor Pathway Inhibitor (TFPI)
RPU58805-50ug	Biomatik Corporation	50ug	495 EUR
Eukaryotic Tissue Factor Pathway Inhibitor (TFPI)
MBS2124279-001mg	MyBiosource	0.01mg	185 EUR
Eukaryotic Tissue Factor Pathway Inhibitor (TFPI)
MBS2124279-005mg	MyBiosource	0.05mg	340 EUR
Eukaryotic Tissue Factor Pathway Inhibitor (TFPI)
MBS2124279-01mg	MyBiosource	0.1mg	515 EUR
Eukaryotic Tissue Factor Pathway Inhibitor (TFPI)
MBS2124279-02mg	MyBiosource	0.2mg	630 EUR
Eukaryotic Tissue Factor Pathway Inhibitor (TFPI)
MBS2124279-05mg	MyBiosource	0.5mg	1205 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody (FITC)
20-abx274012	Abbexa	Ask for price Ask for price Ask for price Ask for price Ask for price	100 ug 10 ug 1 mg 200 ug 50 ug
Tissue Factor Pathway Inhibitor (TFPI) Antibody (FITC)
20-abx274146	Abbexa	Ask for price Ask for price Ask for price Ask for price Ask for price	100 ug 10 ug 1 mg 200 ug 50 ug
Tissue Factor Pathway Inhibitor (TFPI) Antibody Pair
20-abx370061	Abbexa	Ask for price Ask for price	10 × 96 tests 5 × 96 tests
Tissue Factor Pathway Inhibitor (TFPI) Antibody Pair
20-abx370161	Abbexa	Ask for price Ask for price	10 × 96 tests 5 × 96 tests
Tissue Factor Pathway Inhibitor (TFPI) Antibody Pair
20-abx370357	Abbexa	Ask for price Ask for price	10 × 96 tests 5 × 96 tests
Tissue Factor Pathway Inhibitor (TFPI) Antibody Pair
20-abx370374	Abbexa	Ask for price Ask for price	10 × 96 tests 5 × 96 tests
Tissue Factor Pathway Inhibitor (TFPI) Antibody (FITC)
abx274012-25mg	Abbexa	25 mg	975 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody (FITC)
abx274012-5mg	Abbexa	5 mg	412.5 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody (FITC)
abx274146-05ml	Abbexa	0.5 ml	425 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody Pair
abx370061-100g	Abbexa	100 µg	1437.5 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody Pair
abx370161-100g	Abbexa	100 µg	1350 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody Pair
abx370357-100g	Abbexa	100 µg	887.5 EUR
Tissue Factor Pathway Inhibitor (TFPI) Antibody Pair
abx370374-100g	Abbexa	100 µg	1437.5 EUR
Rat Tissue Factor Pathway Inhibitor CLIA Kit
MBS8426981-INQUIRE	MyBiosource	INQUIRE	Ask for price
Recombinant Tissue Factor Pathway Inhibitor (TFPI)
RPU50613-100ug	Biomatik Corporation	100ug	431.2 EUR
Recombinant Tissue Factor Pathway Inhibitor (TFPI)
RPU50613-1mg	Biomatik Corporation	1mg	1911 EUR
Recombinant Tissue Factor Pathway Inhibitor (TFPI)
RPU50613-50ug	Biomatik Corporation	50ug	346.5 EUR
Recombinant Tissue Factor Pathway Inhibitor (TFPI)
RPU44028-100ug	Biomatik Corporation	100ug	517 EUR

CONCLUSIONI
Saranno necessari ulteriori studi per affrontare in modo più completo e sistematico la sicurezza e l’efficacia dei retinoidi topici per il trattamento dell’ectropion nei pazienti con ittiosi; tuttavia, questo caso illustra che il tazarotene topico e altri retinoidi forniscono una potenziale opzione di trattamento per l’ectropion in questa popolazione. Incoraggiamo i medici a esplorare le terapie mediche come alternative all’intervento chirurgico per il trattamento dell’ectropion nei pazienti con ittiosi.